The events of Season 8-9 (With the exception of The Washouts, Sound of Silence, Molt Down and Best Gift Ever), Rainbow Roadtrip and A New Generation are not canon.
Scootaloo gets adopted by Bow Hothoof and Windy Whistles after her original family away.
Big Mac is married to Marble Pie (Note: Applejack and Pinkie are NOT cousins).