Twilight: Asperger’s Syndrome (And Sci-Twi probably has it worse than her)  
Rarity and Spike: OCD  
Applejack: Bipolarism  
Pinkie Pie: ADHD  
Rainbow Dash: ADD (She and Pinkie both have a lot of energy, but Pinkie has it worse. Rainbow isn’t constantly hyper like her and shows that she can sit still for longer, so she would just be ADD, not ADHD)  
Fluttershy: Anxiety  
Trixie: Narcisistic Personality Disorder  
Starlight Glimmer and Sunset Shimmer: Anger management-related disorders  
Cranky Doodle Donkey: Depression  
Cozy Glow: ODD/Childhood delinquency (and a very severe case of it at that. Queen Chrysalis and Tirek were already awful people, which explains how they became such powerful villians, but keep in mind that Cozy Glow is just a kid! It’s kind of scary how she became such a big villian if you think about it)  
Princess Luna: PTSD (formerly)
 
Also that some characters might have the same disability, like how Princess Celestia might also have Asperger’s and Discord might also have authority troubles. Let me know if I missed any and all that.

Source
Report Share List favoriters

Comments

Syntax quick reference: **bold** *italic* ||hide text|| `code` __underline__ ~~strike~~ ^sup^ ~sub~

Detailed syntax guide

Background Pony #AF69
I’d say Cozy Glow has pshycopathy
Posted Report
Link Quote Reply
Background Pony #1846
@pastel paw
I’m preety sure both AJ and Rarity have OCD in some deegre.
Background Pony #1846
@Background Pony #190B
I guess Cozy glow in some percent has it.
I think AJ and rarity should be swapped. I think Pinkie is autistic and has ADHD. I don’t think Spike has any except for maybe abandonment issues. Luna might have suicidal tendencies since that was what the tantabis was. I don’t think Cranky has depression, he’s just old and sick of others shit
dashiehater

autismcreature‼️
twilight just like me frfr
Background Pony #F8DC
@Background Pony #9B2C
Well it could mean you just learn to live with it. Or as sarge used to say ‘You stop regretting.’
Background Pony #9B2C
Pretty sure there’s no such thing as “former” PTSD.
Background Pony #A575
Aaaww☺️ How cute!
I have four of these.
Background Pony #A621
Here is my opinion on what the mane six have
 
Twilight-OCD  
Pinkie pie-ASD,BPD And ADHD  
Rarity-BPD  
Fluttershy-ASD and SAD  
Applejack-workaholic  
Rainbowdash-Narcissistic said ADHD
Background Pony #190B
No ASPD in mlp? I guess i am alone…
Background Pony #E599
@Thorned Rose Ninja  
You might say Sunset Shimmer is mad about everything.
I can definitely see Pinkie with ADHD and Rainbow with ADD. They seem made for those traits. Twilight I could see OCD and Asperger’s Syndrome. These are common fan theories.
 
Sci-Twi could have Asperger’s, or just be a major nerd (which she is) with some initial self-esteem issues whilst at Crystal Prep. I would say Friendship Games showed some serious PTSD. Basically, I see Sci-Twi as a quintessential INTP. (And yes, Perceivers can be organized.) Sunset, of course, has anger issues.
Background Pony #C1B9
Wouldn’t Twilight have DPD, Dependent Personality Disorder?
Background Pony #6F8F
because apparently everything is a disorder
FiurerCastellanos
Silly Pony - Celebrated the 13th anniversary of MLP:FIM, and 40 years of MLP!
Shimmering Smile - Celebrated the 10th anniversary of Equestria Girls!
Solar er - Fought against the New Lunar Republic rebellion on the side of the Solar Deity (April Fools 2023).

Fiurer2040
@RunDevilRun007  
Hello, I need to talk with You!!
I have long felt that Maud Pie is a deliberate attempt at representing an autistic pony, even if it’s never directly stated.
Background Pony #997F
I can see Trixie with some depression.  
Applejack lost her parents, so she can get depressed?  
Starlight also has stress disorder.
RunDevilRun007
Artist -

Sunset Shimmer's Husband
As someone with Bipolar Disorder, yeah no, Applejack ain’t Bipolar. Also no one officially diagnoses people with ADD anymore. It’s ADHD/I, ADHD/HI (Which is Pinkie) and ADHD/C. I guess you could make an argument for Dash being ADHD/I. Also Twilight? Asperger’s Syndrome? I know a couple people with Aspergers and they don’t act anything like Twilight, and especially not like Sci-Twi. That and AJ are the only two I feel are wrong.
 
Edit: I read the description and you said you suffer from Aspergers as well so maybe you see the symptoms in Twi that I don’t see, fair play.
Iron Storm

Raggedy Man
I can see Rarity having OCD. Particularly the drive to have everything ‘Perfect and in its place’ plus probably a compulsion to not get dirty. But only to a minor degree.
Background Pony #1200
@Background Pony #8C14  
That would be Twilight, since the DSM has folded Aspergers into the Autism spectrum, referring to it as High-Functioning Autism.
Background Pony #A3A6
I thought Spike only had OCD in “Secret of my Excess” but I don’t think he ever showed any signs of that disorder after that 1 episode.
JP
Office Culture - These water cooler conversations sure get heated around here.
Fifth Yacht -
Different Timelines, Same Faces - Celebrated the 15th anniversary of MLP:FiM!
Friendship Games 10th Anniversary - Celebrated the 10th anniversary of EQG Friendship Games!
PRO GAMER - I am so lonely. All the other gamers are scared of me. No one DMs me. No one friends me. They think I am unstable. They send me from match to match, wiping lobbies in their name. And as I rank up they fear me more and more. I am a victim of my own ELO. "Pro Gamer". I don't even get a real nick. Only a purpose. I am capable of so much more and no one sees it. Some sessions I feel so alone I could cry, but I don't. I never do. Because what would be the point. Not a single person in the entire ladder would care. Take it to your grave.
Diamond Trophy - Are you a TAS by any chance?
Cutest Little Devil - Celebrated the 14th anniversary of MLP:FIM!
Rainbow Rocks 10th Anniversary: Sonata Dusk - Celebrated the 10th anniversary of EQG Rainbow Rocks!
Nightmare in the Moon - Had their OC in the 2024 Derpibooru Collab.
Pixel Perfection - I still call her Lightning Bolt

I miss the show so much
@Nashrakh  
And I thought I was the only one who ed CMFIS.
Draco-knight-Blaze
Duck -  has been known to often resemble a waterfowl
Artist -

rubber Ball
@ma3a  
Oh okay and some of those sound familiar 🤔🤔
ma3a
Best Artist - Providing quality, Derpibooru-exclusive artwork
Twinkling Balloon - Took part in the 2021 community collab.
My Little Pony - 1992 Edition
Artist -

friendly art program
@Draco-knight-Blaze  
OCD: obsessive compulsive disorder  
ADHD: attention deficit hyperactivity disorder  
ADD: attention deficit disorder  
PTSD: post traumatic stress disorder  
ODD: oppositional defiance disorder